16/10/2023
Excited to announce the publication of the latest scientific research in Liedl’s group about the evolution of immunoglobulin isotypes!
N. Pomarici, R. Cacciato, J. K***t, M. Fernández-Quintero, K. Liedl: Evolution of the Immunoglobulin Isotypes—Variations of Biophysical Properties among Animal Classes
Exploring the fascinating world of antibody diversity, this work sheds light on the evolutionary patterns and relationships among different immunoglobulin isotypes in the vertebrate animal classes.
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The adaptive immune system arose around 500 million years ago in jawed fish, and, since then, it has mediated the immune defense against pathogens in all vertebrates. Antibodies play a central role in the immune reaction, recognizing and attacking external invaders. During the evolutionary process,....