13/04/2026
Tanszékünkről Dr Igaz Nóra, Dr Szőke Krisztina, Dr Bocz Csenge és Dr Kiricsi Mónika vett részt abban a kutatásban, amely a napokban jelent meg "Interactions of IOX1, a histone demethylase inhibitor, with essential metal ions, albumin, and its clay-based nanoformulation" címmel a Dalton Transactions folyóiratban.
Herein, the chemical properties of 5-carboxy-8-hydroxyquinoline (IOX1), a histone lysine demethylase KDM4 inhibitor, were comprehensively characterized in aqueous solution, including its complex formation equilibria with essential metal ions such as Fe(ii), Fe(iii), and Cu(ii). IOX1 shows the follow...