Hébert Lab

Hébert Lab http://www.ncbi.nlm.nih.gov/pubmed/?term=hebert+te
Take a look around... enzymes and ion channels) by a transducer.

In the Department of Pharmacology and Therapeutics at McGill: we to understand how G protein-coupled receptors work and thinks about new ways to develop them as drug targets. Our research is centered broadly around the theme of G protein-coupled signal transduction systems. These signalling systems are activated by agonists that bind to G protein-coupled receptors (GPCRs) leading to the regulation

of effector proteins (e.g. We are interested in 1) basic mechanisms of how these signalling systems are wired, 2) novel signalling complexes and pathways associated with alternative subcellular localization of GPCRs and 3) the roles that these architectural features of signalling complex design might play in the progression or treatment of disease. More recently, we have also become interested in how novel allosteric regulators of these receptors might be developed and tested, here with a focus on inflammatory mediators, their receptors and their roles in health and disease.

Failed state does not even begin to cover it...
02/11/2026

Failed state does not even begin to cover it...

Moderna announced this evening that the Food and Drug Administration (FDA) has refused to initiate a review of its application for an mRNA-based seasonal influenza vaccine.

Planning? Hah!
02/11/2026

Planning? Hah!

Does anyone have a plan for what happens next?

Wow.
02/10/2026

Wow.

Many physicians find chatbots threatening, but that doesn’t mean they’re giving up on medicine.

A good bit of history...
02/10/2026

A good bit of history...

How the Gila Monster Gave the World Ozempic: The creature’s toxic venom revolutionized diabetes treatment.

This!
02/10/2026

This!

The health of a nation reflects the health of a democracy.

The story is not going away...
02/09/2026

The story is not going away...

A controversial Canadian medical paper, which pinned a baby’s death on codeine passed through breastmilk, is under renewed scrutiny a full two decades after it was published. The paper sparked a sweeping shift in global approaches to pain management and breastfeeding guidance for new mothers.

Is financial "innovation" grift? Certainly it is "ensh*ttifying" our world.
02/08/2026

Is financial "innovation" grift? Certainly it is "ensh*ttifying" our world.

Regulating the industry is useful. Shaming it is crucial.

Dropping Amazon Prime in next couple of days. Jeff Bezos really is starting to make Musk look like a good guy. Also, thi...
02/07/2026

Dropping Amazon Prime in next couple of days. Jeff Bezos really is starting to make Musk look like a good guy. Also, this...

The campaign is among the largest anti-ICE protests by workers at a single company since federal agents shot and killed two people in Minneapolis last month.

The hubris is certainly colossal...
02/07/2026

The hubris is certainly colossal...

Colossal Biosciences aims to freeze millions of animal samples in the hope of saving endangered species, or one day resurrecting them.

Whereas in Canada, we're simply underfunding science and making peer review a joke.
02/06/2026

Whereas in Canada, we're simply underfunding science and making peer review a joke.

The Trump administration seems to want less clean energy and more preventable diseases

Cool review!
02/06/2026

Cool review!

Investigations of the genetic basis of coronary artery disease have led to advances in mechanistic insights, therapeutics, prevention, and risk prediction. Indeed, most contemporary medicines for c...

Finally!
02/06/2026

Finally!

Enlicitide decanoate, an oral proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitor, was shown to reduce low-density lipoprotein (LDL) cholesterol levels in a phase 2 trial; longer-term d...

Address

Department Of Pharmacology And Therapeutics, McGill University, Room 1303, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler
Montreal, QC
H3G1Y6

Telephone

+15143988803

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