Hébert Lab

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Hébert Lab http://www.ncbi.nlm.nih.gov/pubmed/?term=hebert+te
Take a look around... enzymes and ion channels) by a transducer.

In the Department of Pharmacology and Therapeutics at McGill: we to understand how G protein-coupled receptors work and thinks about new ways to develop them as drug targets. Our research is centered broadly around the theme of G protein-coupled signal transduction systems. These signalling systems are activated by agonists that bind to G protein-coupled receptors (GPCRs) leading to the regulation of effector proteins (e.g. We are interested in 1) basic mechanisms of how these signalling systems are wired, 2) novel signalling complexes and pathways associated with alternative subcellular localization of GPCRs and 3) the roles that these architectural features of signalling complex design might play in the progression or treatment of disease. More recently, we have also become interested in how novel allosteric regulators of these receptors might be developed and tested, here with a focus on inflammatory mediators, their receptors and their roles in health and disease.

Important review!
09/25/2026

Important review!

Twenty-five years after the draft of the human genome sequence, genomics has revolutionized many areas of biology, the diagnosis of familial and early-onset diseases, and the development of targete...

This is cool.
09/25/2026

This is cool.

Networks of bioelectronic sensors and actuators enable closed-loop therapies that connect distant, related physiological dynamics. Currently, device interactions are limited by communication methods that inefficiently pe*****te tissue and require bulky ...

What to do?
09/25/2026

What to do?

Uh-oh... no wait it's OK, back to doomscrolling about AI!
09/25/2026

Uh-oh... no wait it's OK, back to doomscrolling about AI!

No, it’s not aliens, but a phenomenon caused by magnetic activity that astronomers have never before been able to pin on a specific planet.

The tools are coming? Some of my colleagues are already running several AI agents in their work.
09/25/2026

The tools are coming? Some of my colleagues are already running several AI agents in their work.

Artificial-intelligence systems can generate hypotheses, design experiments and analyse data — but humans still need to decide what makes sense.

Half-baked, as usual...
09/25/2026

Half-baked, as usual...

Les facultés existantes sont les mieux placées pour former de nouveaux médecins de manière rapide et à coût moindre, écrivent ici les doyens des quatre facultés de médecine du Québec.

Let's just say I am concerned...
09/25/2026

Let's just say I am concerned...

There is growing concern that AI can blunt memory and reasoning. But science shows ways to keep the brain sharp.

Wow!
09/24/2026

Wow!

A systematic repurposing pipeline identified uterus-selective tocolytics with efficacy in human myometrium and preclinical models.

Worth reading!
09/24/2026

Worth reading!

My patient didn’t need a prescription drug; she needed a human to understand her.

Adresse

Department Of Pharmacology And Therapeutics, McGill University, Room 1303, McIntyre Medical Sciences Building, 3655 Promenade Sir William Osler
Montreal, QC
H3G1Y6

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