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Klein Lab - Equine Reproduction Research and More

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Deutschland
Mariensee
Klein Lab - Equine Reproduction Research and More

Welcome to the Klein Lab. Our research revolves around the Physiology of Early Pregnancy in the Horse.

Dr. Claudia Klein originally hails from Germany where she obtained her veterinary degree. Following a year in research and a year as Clinical Instructor, she relocated to Gainesville, Florida, US in 2006 to pursue a residency in Equine Reproduction. In 2008 Dr. Klein moved to Lexington, KY to pursue a PhD on Early Equine Pregnancy in the mare. In late 2012 she joined the College of Veterinary Medicine at the University of Calgary as Assistant Professor of Theriogenology.

19/06/2026

Always nice to see familiar faces again! Carolina Herrera 🐮 🇨🇭

18/06/2026

Got to see the traditional three-stage farming in the Bregenzerwald (Austria). This type of keeping milking cattle is even considered an intangible UNESCO World Heritage Site.
Cows spend the winter in the local village, spring is spent outside the village where cows have free access to pasture and summer is spent up in the mountains.
They are only fed hay (no silage) and the milk is used for cheese production.

16/06/2026

Goats, cattle, chickens, ponies, and donkeys make for nice strolls. 🐐 🐄 🐎 🫏 🐓

16/06/2026

This year’s annual meeting of the Arbeitsgemeinschaft Embryotransfer deutschsprachiger Länder is taking place in Austria. The scenery is stunning.

26/05/2026

It is common practice in IVF settings to exclude oocytes displaying a granulated ooplasm. This study compared the protein and lipid landscape, as well as the developmental competence, of immature cattle oocytes with either granulated or homogeneous ooplasm.

Result: Granulated oocytes present a distinct, lipid‑rich phenotype with configured peroxisomal and mitochondrial pathways and presented an enhanced developmental competence, i.e. a higher blastocyst rate following IVF in a serum-free IVF set up.

🐮 🐄 🔬 👩‍🔬

17/05/2026

Definitely worth watching. 🐎 🎥

18/04/2026

The waiting game of peer review…. Finding reviewers….

14/04/2026

Katerina defended her PhD work today. The decoration of the doctoral hat reflects the main topic of her work: physiology of boar s***m. 🐷 🐽 🐖

10/04/2026

Equine endometrial fibrosis is an interesting topic……. We recently looked at the role of MFGE8 using single cell sequencing and in situ hybridization.

“Milk fat globule EGF and factor V/VIII domain containing (MFGE) as a novel player in equine endometrial fibrosis” 🐎

21/11/2025

In vitro production of bovine embryos still has its limitations, such as low blastocyst rate and lower embryo quality, resulting in lower pregnancy rates following transfer compared to in vivo produced embryos. Transcriptional studies comparing both types of embryos mainly utilize oocytes retrieved from slaughterhouse material for IVP, thereby introducing the possibility, that differences between IVP and in vivo embryos are in part attributable to differing sources of oocytes.

The present study compared the proteome of oocytes retrieved from slaughterhouse material, with and without a period of in vitro maturation, and in vivo matured oocytes obtained from superovulated donor cattle.

Main finding: In vitro matured oocytes were characterized by an overall enhanced translational activity affecting mainly proteins involved in energy metabolism, transcription and translation, and oocyte activation. Deregulation of the proteome in in vitro matured oocytes likely negatively affects subsequent developmental events.

Adresse

Mariensee

Webseite

http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/50542854/?sort=date&direction=ascending

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