10/09/2026
Systematic review found that for adults with stroke, modified constraint induced movement therapy may improve upper-limb function compared to conventional therapy
π· Modified Constraint Induced Movement Therapy (mCIMT) involves using the affected limb intensively over multiple weeks, while restricting the use of the non-affected limb. Intensive, repetitive, task-specific training is performed with the affected limb only. mCIMT is different from CIMT as it follows less rigid protocols and allows for the optimisation of time and training intensity. It is frequently used instead of, or combined with, conventional therapy.
π· This systematic review aimed to estimate the effects of mCIMT compared to conventional therapy on upper-limb function in people with stroke.
π· The study included randomised controlled trials, adults (18 years+) with stroke of any chronicity that used of mCIMT intervention compared to conventional therapy. Trials were included if they measured upper-limb function. The primary outcome was upper-limb function, measured using the Fugl-Meyer Upper-Extremity tool. Outcome measures were expressed as Hedges g. Trial quality was evaluated using the Cochrane risk of bias 2.0 tool. Certainty of evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.
π· 10 trials (422 participants) were included in the meta-analyses. Participants were aged from 39 to 94 and had acute stroke (2 trials), chronic stroke (5 trials) or unclear chronicity (3 trials). Interventions ranged from 30-180 minutes, 3-7 days/week for 2-12 weeks.
π· There was low certainty evidence that mCIMT was better than conventional therapy for upper limb function (Hedges g: 1.25, 95% CI: 0.53 to 1.96, I2 = 90%). Subgroup analyses were performed but these had wide confidence intervals and were underpowered.
π· This review suggests mCIMT may improve upper-limb function compared to conventional therapy for adults following stroke.
Access the full summary on PEDro: https://pedro.org.au/english/systematic-review-found-that-for-adults-with-stroke-modified-constraint-induced-movement-therapy-may-improve-upper-limb-function-compared-to-conventional-therapy/