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YAM Laboratory focuses on the study of liver cancer, particularly on how tumor microenvironment modulated by extracellular vesicles contributes to cancer metastasis.

📝We are excited to share our latest study, which uncovers the pivotal role of small extracellular vesicle (sEV)-delivere...
17/08/2026

📝We are excited to share our latest study, which uncovers the pivotal role of small extracellular vesicle (sEV)-delivered nidogen 1 (NID1) in driving liver cancer progression and metastasis. Our research demonstrates that NID1-enriched sEVs enhance oncogenic behaviors in hepatocellular carcinoma (HCC) through activation of the TGM3-mediated YAP/TAZ signaling cascade, underscoring the sEV-NID1-TGM3 axis as a promising therapeutic target for HCC. Importantly, we show that targeting NID1 with a novel monoclonal antibody effectively suppresses tumor growth and metastasis in multiple HCC models.

https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev2.70359

📢Excited to share our latest review: Machine Learning-Enhanced Extracellular Vesicle Omics in Oncology! Discover how mac...
16/08/2026

📢Excited to share our latest review: Machine Learning-Enhanced Extracellular Vesicle Omics in Oncology! Discover how machine learning is unlocking the potential of EVs as liquid biopsy biomarkers for early cancer detection, prognosis, and treatment response. We provide a comprehensive overview of advances across transcriptomics, proteomics, metabolomics, and lipidomics, discuss key challenges, and highlight emerging directions like single-vesicle profiling and multimodal integration.

https://link.springer.com/article/10.1186/s12951-026-04342-0

An interactive 2-day meeting at University of Oxford 🇬🇧
04/07/2026

An interactive 2-day meeting at University of Oxford 🇬🇧

Our team recently visited the Second Affiliated Hospital of Harbin Medical University for an enriching academic exchange...
30/05/2026

Our team recently visited the Second Affiliated Hospital of Harbin Medical University for an enriching academic exchange. We enjoyed insightful presentations from postdoctoral fellows representing HKU, CUHK, PolyU, and Harbin Medical University. The trip also included visits to other institutions and innovative startups, along with site tours and delicious local cuisine. An inspiring and enjoyable experience for all ☺️

The Hong Kong Scholars Annual Symposium took place at the Hong Kong University of Science and Technology on May 16. This...
17/05/2026

The Hong Kong Scholars Annual Symposium took place at the Hong Kong University of Science and Technology on May 16. This annual event provides a platform for Hong Kong Scholars to showcase their latest research conducted in Hong Kong. We are excited to welcome Jiankun as the new member of our team and look forward to seeing him present at next year’s symposium!

I am truly honored to receive the Outstanding Research Student Supervisor Award. Over the past 21 years as a supervisor,...
01/05/2026

I am truly honored to receive the Outstanding Research Student Supervisor Award. Over the past 21 years as a supervisor, I have been fortunate to work with dedicated students and an incredibly supportive team. This moment is made even more meaningful by the presence of Professor Wendy Hsiao, who was my supervisor 30 years ago, at the ceremony. My heartfelt thanks to everyone who has been part of this journey!

Celebrating Excellence at the HKUMed Faculty Prize Presentation Ceremony on February 26, 2026🎉Congratulations to Samuel ...
02/03/2026

Celebrating Excellence at the HKUMed Faculty Prize Presentation Ceremony on February 26, 2026🎉
Congratulations to Samuel (PhD student) for receiving the Chan To Haan Prize for Research Postgraduate Students in Pathology, Jeremy (summer intern who is now in Year 2 MBBS) for earning the Tse Chan Fai Prize in Liver Cancer Research, and Amy (BBMS final year project student) for making the Dean’s List. We are proud of your achievements🎊

Feeling grateful for the birthday celebration from my amazing team 🎉🎊🎈🎂😊
13/01/2026

Feeling grateful for the birthday celebration from my amazing team 🎉🎊🎈🎂😊

🎄Celebrated a festive Christmas lunch with my team, exchanging gifts with our Secret Santa🎅🏼 Wishing everyone a joyful C...
23/12/2025

🎄Celebrated a festive Christmas lunch with my team, exchanging gifts with our Secret Santa🎅🏼 Wishing everyone a joyful Christmas and a Happy New Year!

Enjoyed a two-day visit to the University of Macau to reconnect with my former Research Assistant Professor, Susan. Had ...
23/12/2025

Enjoyed a two-day visit to the University of Macau to reconnect with my former Research Assistant Professor, Susan. Had an engaging and productive discussion with her team about ongoing research. The campus is truly beautiful!

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Block T, Queen Mary Hospital, Pokfulam
Hong Kong
0000

Telephone

+85222552706

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