Tamed Cancer - ERC StG Grant

Tamed Cancer - ERC StG Grant The aim of the research is to design a controller which administers cancer specific drug and thereby

The Research Field – Medical & Engineering Interdisciplinary Research
- The aim of antiangiogenic therapy is to stop the angiogenesis process (i.e. vascular system development) of the tumor; hence, to stop tumor growth
- Modern robust control algorithms provides automated drug administration
The Research Concept – Present & Future
- In the present clinical practice there are general protocols f

or cancer therapies (like chemotherapy, radiotherapy)
- these treatments have frequent and serious side effects
- they are not cancer specific and not personalized for the patients
- the treatment cost is low; however the usage is non-optimized
- Our concept: controller-based individualized treatment
- these treatments have virtually no side effect
- it provides personalized administration of cancer specific (antiangiogenic) drugs
- the treatment cost is duly low due to the optimal drug administration
Objectives of the Research – Model Identification & Controller Design
- Create mathematical tumor growth model under angiogenic inhibition based on animal experiments
- Create constant and variable quasi-continuous low-dosage therapy protocol
- Design optimal robust control algorithms for continuous low-dosage therapy
Impact of the Research – Opening New Horizons in Cancer Treatment
- Improve cancer therapy efficiency
- Decrease treatment costs
- Minimize side effects of the therapy
- Improve the patient's quality of life (QoL)
The Research Group
- Principal Investigator: Prof. Dr. Levente Kovács (Physiological Controls Group, Obuda University, Budapest, Hungary, Web: http://physcon.uni-obuda.hu/, Email: [email protected])
- 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary

Melánia Puskás, student member of the Physiological Controls Research Center, has won the first place in the medical inf...
30/04/2021

Melánia Puskás, student member of the Physiological Controls Research Center, has won the first place in the medical informatics section of the National Scientific Student Competition (Országos Tudományos Diákköri Konferencia). The title of her thesis is "Parameter estimation of physiological processes using artificial intelligence", her supervisor is Dr. Dániel András Drexler.

Results in Brief article on the CORDIS website:
21/04/2021

Results in Brief article on the CORDIS website:

A new mathematical tumour model represents a step change in treatment, advancing a reference model more than 20 years old.

Habilitation of Dr. Tamas Ferenci of PhysCon.
27/05/2019

Habilitation of Dr. Tamas Ferenci of PhysCon.

Prof. Kovacs holds his presentation at the Hungarian Academy of Sciences today - including the latest findings of PhysCo...
22/05/2019

Prof. Kovacs holds his presentation at the Hungarian Academy of Sciences today - including the latest findings of PhysCon Lab.

The negotiations at the University of Pécs went very successfully. New collaborations are expected in the near future. P...
01/05/2019

The negotiations at the University of Pécs went very successfully. New collaborations are expected in the near future. Prof. Karádi from and Prof. Odry from have invited Physcon for a lunch as well.
Prof. Kovács of Physcon was a prosperous meeting with the dean of the Medical School of .

Brainstorming of PhysCon, Hungarian Diabetes Association, Heim Pal Children's Hospital and Harvard's Biomedical Systems ...
02/04/2019

Brainstorming of PhysCon, Hungarian Diabetes Association, Heim Pal Children's Hospital and Harvard's Biomedical Systems Engineering Research Group.

Negotiation between PhysCon and BioTech Centers of Obuda University, 77 Elektronika Ltd., Heim Pal Children's Hospital a...
01/04/2019

Negotiation between PhysCon and BioTech Centers of Obuda University, 77 Elektronika Ltd., Heim Pal Children's Hospital and Harvard's Biomedical Systems Engineering Research Group went really well!
New common research collaboration is on the way - further details will be available soon.

A great lecture was held by Prof. Amit Bhatt hosted by our PhysCon Research Center. Prof. Bhatt of ARM and Treepie is an...
15/03/2019

A great lecture was held by Prof. Amit Bhatt hosted by our PhysCon Research Center.
Prof. Bhatt of ARM and Treepie is an experienced hardware and processor designer currently focusing on embedded AI applications.
Hopefully, common collaboration can be built up on the field of Biomedical Engineering as well.

PhysCon at ATTD 2019!The PhysCon group was represented by the head of the group Prof. Kovács at the biggest world class ...
02/03/2019

PhysCon at ATTD 2019!

The PhysCon group was represented by the head of the group Prof. Kovács at the biggest world class diabetes congress held in Berlin, Germany this year.
Prof. Kovács presented a poster summarizing the latest findings of our group regarding diabetes researches. Successful negotiation was made with top scientists and industrial partners as well.

21/02/2019

Special Session proposals have sent to IEEE SMC 2019.
Excited to get good news about their acceptance!
Further details are expected in March.

21/02/2019

The ERC grant of Obuda University at the Italian mathematics congress

Rome held the bi-annual congress of the Italian Society of Applied and Industrial Mathematics (SIMAI) between 2-6 of July, 2018. The Physiological Controls Research Center (PhysCon) of Obuda University was invited by its head, Prof. Dr. Levente Kovacs as a keynote lecturer in the biomathematics session of the congress on the very first day of it (2nd of July, 2018).
The SIMAI’s healthcare oriented mathematical session was organized by the SIMAI’s host institution, La Sapienza University together with the CNR Rome research institute and was sponsored by the European Mathematical and Theoretical Biology Society (ECMTB). The PhysCon was represented by its leader Prof. Dr. Levente Kovács and its post-doc Dr. Daniel Drexler.

21/02/2019

Participation on AQTR is always a good way to get new connections and possible international collaborators.

From 24th of May to 26th of May, 2018, Cluj-Napoca held the International Conference on Automation, Quality and Testing, Robotics (AQTR 2018). The conference, that is organized in every two years, had a special section organized by PhysCon group.

The PhysCon group jointly organized a special session under the name of „Modern control methodologies and modeling techniques” with the Automation and Control department of Technical University Cluj-Napoca, with the lead of Dr. Levente Kovács and Dr. Éva Dulf.

The aim of the section was to present the applicability of modern control methods, such as fractional, Tensor Product, or LMI methodologies on physiological and chemical engineering fields.

On top of presenting the recently developed results of the ERC project, research with the Hungarian Diabetes Association was also presented to the audience. The PhysCon group was represented by Dr. Levente Kovács and the young researcher Tamás Gönczy on the conference.

Cím

Bécsi út 96/B
Budapest
1034

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