22/05/2026
We are pleased to announce the successful completion of the Site Acceptance Tests (SAT) of the new Electron FLASH SIT platform installed at CAPIR – University of Catania. This important milestone was achieved through the collaboration between INFN-LNS (Giacomo Cuttone, Giada Petringa, Roberto Catalano), CNR-IBSBC (Giorgio Russo), UNICT (Rosalba Parenti, Giovanni Li Volti) and Cannizzaro Hospital (Mariagabriella Sabini, Annalisa Muscato), within the framework of the Pilot 4.4 of ANTHEM – AdvaNced Technologies for Human-centrEd Medicine project
The system will enable irradiations in Electron FLASH mode, an emerging frontier in radiation therapy based on ultra-high dose rate (UHDR) beam delivery, with the potential to spare healthy tissues while maintaining high tumour control effectiveness. The INFN-LNS dosimetry group played a key role in the characterization and dosimetric commissioning activities of the machine, including beam parameter verification, absolute and relative dosimetry, and validation of FLASH operational conditions required for upcoming radiobiological studies.
With the successful completion of the SAT activities, the facility is now ready for in vitro and in vivo irradiation campaigns aimed at investigating the FLASH effect, one of the most innovative and promising topics in modern radiobiology research. This achievement represents a further step forward in the development of advanced technologies for radiation therapy and in strengthening the Sicilian research infrastructure in medical physics, radiobiology, and biomedical applications of ionizing radiation.