05/02/2026
細胞質RNAの電荷がクロマチン構造の制御や細胞核の形成に影響を与えることを示した論文が、Molecular Biology of the Cell誌に掲載されました🎉
https://molbiolcell.org/doi/10.1091/mbc.E25-09-0440
この研究はラボの卒業生の池田さん、田中くん、正法地くんが中心に進めてくれた研究です😁
Our paper is out!!
https://molbiolcell.org/doi/10.1091/mbc.E25-09-0440
The paper describes a novel role for RNA. Its charge status contributes to chromatin remodeling and nuclear assembly in Xenopus eggs.
The small hypercondensed s***m nucleus undergoes a dramatic transformation into a large round pronucleus with relaxed chromatin during the brief cleavage period in metazoan embryos, enabling the activation of chromatin functions necessary for subsequent development. However, it remains unclear wheth...