Korea University BK21 program: Department of Biomedical Sciences

16/06/2026

2026 4단계 BK21 융합중개의과학 교육연구단 및 대학원 의과학과 하계 워크샵. 2026년 7월 6일(월). 고려대학교 의과대학 320호 및 유광사 홀.

상세 프로그램 링크
https://bk21kumedicine.korea.ac.kr/bk21kumedicine/board/notice.do?mode=view&articleNo=811723

16/06/2026

워크샵 참석자 전원에게 귀여운 호의랑 티셔츠를 드립니다.

21/05/2026

[4단계 BK21 융합중개의과학교육연구단] SNS 콘텐츠 참여 이벤트 안내_6월15일(월)까지 접수

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14/05/2026

14/05/2026

Easy Isolation of Extracellular Vesicles (EVs) Using Cryo-Photocrosslinked Hydrogel

25/02/2026

Mitochondrial Gene Editing : Opening a New Horizon in the Treatment of Hereditary Blindness(LHON)

25/02/2026

Mitochondrial Gene Editing : Opening a New Horizon in the Treatment of Hereditary Blindness(LHON)

25/02/2026

Opening the Future of Drug Development with a Multi-Brain Organoid Signal Simultaneous Measurement-Based Drug Screening System

30/09/2022

J Korean Med Sci. 2022 Mar 21;37(11):e88. doi:10.3346/jkms.2022.37.e88.

Complications of Nasopharyngeal Swabs and Safe Procedures for COVID-19 Testing Based on Anatomical Knowledge

Dai Hyun Kim 1 2, Dasom Kim 2, Jee Won Moon 3, Sung-Won Chae 4, Im Joo Rhyu 2 5

Abstract
Nasopharyngeal swabs have been widely to prevent the spread of coronavirus disease 2019 (COVID-19). Nasopharyngeal COVID-19 testing is a generally safe and well-tolerated procedure, but numerous complications have been reported in the media. Therefore, the present study aimed to review and document adverse events and suggest procedural references to minimize preventable but often underestimated risks. A total of 27 articles were selected for the review of 842 related documents in PubMed, Embase, and KoreaMed. The complications related to nasopharyngeal COVID-19 testing were reported to be rarely happened, ranging from 0.0012 to 0.026%. Frequently documented adverse events were retained swabs, epistaxis, and cerebrospinal fluid leakage, often associated with high-risk factors, including severe septal deviations, pre-existing skull base defects, and previous sinus or transsphenoidal pituitary surgery. Appropriate techniques based on sufficient anatomical knowledge are mandatory for clinicians to perform nasopharyngeal COVID-19 testing. The nasal floor can be predicted by the line between the nostril and external ear canal. For safe testing, the angle of swab insertion in the nasal passage should remain within 30° of the nasal floor. The swab was gently inserted along the nasal septum just above the nasal floor to the nasopharynx and remained on the nasopharynx for several seconds before removal. Forceful insertion should be attempted, and alternative examinations should be considered, especially in vulnerable patients. In conclusion, patients and clinicians should be aware of rare but possible complications and associated high-risk factors. The suggested procedural pearls enable more comfortable and safe nasopharyngeal COVID-19 testing for both clinicians and patients.

Keywords: COVID-19 Testing; Complications; Nasopharyngeal Swab; Procedural Reference; Risk Factors.

3Department of Otorhinolaryngology-Head and Neck Surgery, Korea University G**o Hospital, Korea University Medicine, Seoul, Korea.

15/08/2022

Nat Metab. 2022 Jul 28. doi: 10.1038/s42255-022-00609-6. Online ahead of print.

Systemic induction of senescence in young mice after single heterochronic blood exchange

Ok Hee Jeon 1 2, Melod Mehdipour 3, Tae-Hwan Gil 4, Minha Kang 4, Nicholas W Aguirre 5, Zachery R Robinson 3, Cameron Kato 3, Jessy Etienne 3, Hyo Gyeong Lee 4, Fatouma Alimirah 5, Vighnesh Walavalkar 6, Pierre-Yves Desprez 5, Michael J Conboy 3, Judith Campisi 7 8, Irina M Conboy 9

Abstract
Ageing is the largest risk factor for many chronic diseases. Studies of heterochronic parabiosis, substantiated by blood exchange and old plasma dilution, show that old-age-related factors are systemically propagated and have pro-geronic effects in young mice. However, the underlying mechanisms how bloodborne factors promote ageing remain largely unknown. Here, using heterochronic blood exchange in male mice, we show that aged mouse blood induces cell and tissue senescence in young animals after one single exchange. This induction of senescence is abrogated if old animals are treated with senolytic drugs before blood exchange, therefore attenuating the pro-geronic influence of old blood on young mice. Hence, cellular senescence is neither simply a response to stress and damage that increases with age, nor a chronological cell-intrinsic phenomenon. Instead, senescence quickly and robustly spreads to young mice from old blood. Clearing senescence cells that accumulate with age rejuvenates old circulating blood and improves the health of multiple tissues.

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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A single transfer of blood from old male mice is shown to induce cellular and tissue senescence in young animals, unless old mice are treated with senolytic drugs before blood exchange.