Laboratory of Applied Biotechnology CNBM UAM

04/01/2025

📢 New Publication Alert!

We are excited to share our latest research published in Journal of Zhejiang University SCIENCE B:
"Pig meniscus single-cell sequencing reveals highly active red zone chondrocyte populations involved in stemness maintenance and vascularization development"

Meniscus injuries are a common challenge, and current treatments often fall short in promoting effective healing. In this study, we provide critical evidence supporting the use of pigs as a biological model for meniscal degeneration and for developing advanced orthopaedic therapies.

Moreover, our research confirms that the cellular composition of the pig meniscus closely resembles that of humans, further validating pigs as a robust model for orthopaedic research.

📖 Read more here:

20/09/2024

🌟 Exciting News from the 8th Collagen Symposium in Freiburg! 🌟

We had the pleasure of presenting our latest research entitled "Development of a Porcine Decellularized Extracellular Matrix (dECM) Bioink for 3D Bioprinting of Meniscus Tissue Engineering: Formulation, Characterization, and Biological Evaluation" The lecture hall was packed, and we were thrilled by the lively discussion and insightful questions from attendees.

Thank you to everyone who attended and contributed to such an engaging session. We are excited about the future of tissue engineering and the incredible advancements being made in the field. Stay tuned for more updates!

03/09/2024

Our Tomek has just successfully defended the first-ever PhD in Materials Engineering at Uniwersytet im. Adama Mickiewicza w Poznaniu! 🎉 We are beyond proud of his incredible achievement and hard work. Congratulations, Tomek! 🚀👨‍🎓

Pierwszy doktorat w dyscyplinie Inżynieria Materiałowa na UAM. Dziś w Sali im. Stefana Jurgi odbyła się obrona doktoratu Tomasza Szymańskiego z Laboratory of Applied Biotechnology CZT UAM. Promotorem pracy jest prof. dr hab. inż. Jakub D. Rybka, MBA a promotorem pomocniczym dr Adam Mieloch. Doktorat pt:” Application of nanomaterials in cartilage tissue engineering” obroniony, stopień doktora nadany.

Doktorowi Szymańskiemu gratulujemy!

01/09/2024

Hey everyone! 🎉

We have some amazing news to share! This weekend, our fantastic team member, Tomek Szymański said "I do" to his love, Bogna! 💍❤️

On behalf of the entire team, we want to send our warmest congratulations to the newlyweds! 🎊🎉 Wishing you a lifetime full of happiness, love, and beautiful moments together.

And there’s more exciting news! This Tuesday, September 3rd at 12:00 PM in Centrum Nanobiomedyczne UAM, Tomek will be defending his PhD thesis entitled "Application of nanomaterials in cartilage tissue engineering". Let’s all send him our support as he takes on this next big step! 💪🎓

Tomek, we’re so happy to share in these special moments with you! 💖 May each day be as wonderful as the ones you're celebrating.

Sending lots of love! ✨🥂

28/08/2024

🔬Dołącz do zespołu prof. dr. hab. inż. Jakuba D. Rybki, MBA, aby rozpocząć studia doktoranckie w Laboratory of Applied Biotechnology CZT UAM!

📚Poszukujemy absolwenta/-tki studiów II stopnia biologii, biotechnologii lub kierunków pokrewnych, gotowego rozpocząć studia doktoranckie w dziedzinie biologii molekularnej (scRNA-seq, transkryptomika przestrzenna), w projekcie SONATA 19 "Czy metformina działa kardioprewencyjnie w mysim modelu autoimmunizacyjnego zapalenia mięśnia sercowego? Ocena mechanizmu z wykorzystaniem analiz multiomicznych". Projektem kieruje dr inż. Monika Stefańska.

📑 Opis projektu:https://www.ncn.gov.pl/sites/default/files/listy-rankingowe/2023-09-15-akizood8c/streszczenia/605316-pl.pdf
📜 Informacje o konkursie: https://www2.ncn.gov.pl/baza-ofert/?akcja=wyswietl&id=225644
📅 Ostatni dzień na nadsyłanie zgłoszeń: 26 września 2024 r., godzina 16:00!

25/07/2024

We are thrilled to share the pleasure of our recent seminar at the Center for Artificial Intelligence, UAM! It was an incredible experience to present our research and explore how biotechnology and artificial intelligence are building bridges between scientific disciplines.

🔬🤖 Our seminar highlighted the groundbreaking innovations emerging from the intersection of these fields, showcasing how interdisciplinary collaboration is paving the way for future advancements. We discussed how AI is and will transform biotechnology research and shared insights on the latest developments.

Thank you to everyone who joined us and contributed to the enriching discussions. We're excited about the future possibilities and look forward to continuing this journey of innovation and collaboration!

17/07/2024

Inspiring Conference at Stanford University!

The conference was organized by US-Polish Trade Council. It brought together academia, business, and government to discuss Polish-American collaboration and engage in inspiring conversations!

The Uniwersytet im. Adama Mickiewicza w Poznaniu delegation was led by Vice-Rector prof. Michał Banaszak and included: prof. Krzysztof Dyczkowski, prof. Krzysztof Jassem, prof. Artur Stefankiewicz, and prof. Jakub D. Rybka.

It was great to see a strong team from Poznań at Stanford University‼️ Poznań was also represented by: Politechnika Poznańska (prof. Teofil Jesionowski and dr Magdalena HRYB), Uniwersytet Przyrodniczy w Poznaniu (prof. Piotr Goliński) , Miasto Poznań (Katja Lozina), Kostrzyńsko-Słubicka Specjalna Strefa Ekonomiczna S.A. (Magdalena Hilszer), Żabka Polska (dr Tomasz Glowacki) and DomData AG sp. z o. o. (Radosław Mączyński).

It was surely a great time!

08/07/2024

🚀 Groundbreaking Research Alert! 🚀

We are proud to announce the publication of our latest study, showcasing a novel, scalable, and cost-efficient process for dECM extraction from porcine meniscus, specifically tailored for bioink preparation and 3D bioprinting.

Key Achievements:
🔹 Developed an innovative protocol combining homogenisation, hydrolysis, supercritical CO2 (scCO2) extraction, and lyophilisation.
🔹 Maintained native compounds and biocompatibility, ensuring optimal printability.
🔹 Created a conducive environment for cell proliferation and differentiation towards a meniscus-like phenotype.
🔹 Implemented an economically and ecologically friendly approach, reducing reliance on solvents, detergents, and expensive enzymes.
🔹 Achieved substantial DNA reduction and proposed a broader assessment of decellularisation effectiveness beyond DNA content alone.

This research represents a significant step forward in tissue engineering and regenerative medicine, challenging existing paradigms and setting new standards for decellularisation processes.

We invite you to explore our findings and join the conversation on how this innovation can transform the future of bioengineering.

Read more in our latest publication and stay connected for further updates!

This study aims to present an easily scalable, cost-efficient process of dECM extraction from porcine meniscus, dedicated to bioink preparation and 3D bioprinting. Due to its cartilage like structu...

24/05/2024

🎉 Exciting News! 🎉
NEW Research Area Opened in the Laboratory of Applied Biotechnology CZT UAM

We are thrilled to announce that our laboratory has received a new research grant (SONATA19 by Narodowe Centrum Nauki) for an innovative project titled: "Is metformin having a cardioprotective role in mouse model of autoimmune myocarditis. Evaluation of the mechanism of action using multiomics approach."

This cutting-edge study will explore the potential cardioprotective effects of metformin in a mouse model of autoimmune myocarditis, utilizing a comprehensive multiomics approach to unravel the underlying mechanisms. Our team (with dr inż. Monia Stefanska as a PI) is eager to embark on this journey and contribute to the understanding of how metformin might protect the heart in autoimmune conditions.

Stay tuned for updates as we dive into this exciting new research tasks. Thank you for your continued support! 🧬❤️🔬



https://www.ncn.gov.pl/sites/default/files/listy-rankingowe/sonata-19_lr_wszystko.pdf

25/04/2024

Recently, we had the fantastic opportunity to showcase the achievements of our scientific team in Pobiedziska, near Poznań. There's nothing quite like presenting to a room full of enthusiastic attendees – their energy truly uplifts the spirit of every presenter!
A huge thank you to everyone who came out to support us in Biblioteka w Pobiedziskach and for the warm reception we received from Seniorzy Gminy Pobiedziska. It was a reminder of how collective excitement can make special moments even more memorable.
Here’s to many more successful gatherings and the continuous growth of our community! 🚀

10/04/2024

🌟 Zapraszamy wszystkich chętnych na Wykład prof. Jakub D. Rybka! 🌟

Pobiedziski Uniwersytet Sąsiedzki zaprasza na wykład profesora Jakuba Dalibora Rybki
Szczegóły na plakacie

27/03/2024

🔬 Flashback to a Milestone Moment! 🔬

Throwing it back to an unforgettable lecture at Central European BioForum in Warsaw where we had the privilege to present our first biotech spinoff company of Uniwersytet im. Adama Mickiewicza w Poznaniu „SpinBionic"! 🇵🇱 It was an incredible opportunity to share our vision, innovations, and the journey behind our pioneering endeavors in biotechnology and material science! The energy and enthusiasm from the audience were truly inspiring. Grateful for the support and looking forward to more groundbreaking moments ahead!