Natural and Life Sciences Communications

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Natural and Life Sciences Communications วารสารมหาวิทยาลัยเชียงใหม่

🎉 Congratulations Abed et al. on your new publication!🦷𝚃𝚒𝚝𝚕𝚎: Molecular Interplay Between miRNA-155 and Chemokines CCL2/...
21/09/2026

🎉 Congratulations Abed et al. on your new publication!
🦷𝚃𝚒𝚝𝚕𝚎: Molecular Interplay Between miRNA-155 and Chemokines CCL2/CXCL8 in Gingival Crevicular Fluid (GCF) in Gingivitis
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Farah Badri Abed, Ehab Qasim Talib*, and Dunya Abdullah Mohammed
🔗Read via: https://doi.org/10.12982/NLSC.2026.099
🔵𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
This study reveals that gingivitis is characterized by miRNA-155 suppression coupled with strong CCL2-CXCL8 synergy, identifying a novel regulatory mechanism that balances immune cell recruitment with controlled inflammatory responses in early periodontal disease

🎉 Congratulations Kanjanasingh  et al. on your new publication!🌿𝚃𝚒𝚝𝚕𝚎: Occupational Health Risks from Pesticide Exposure...
18/09/2026

🎉 Congratulations Kanjanasingh et al. on your new publication!
🌿𝚃𝚒𝚝𝚕𝚎: Occupational Health Risks from Pesticide Exposure: Evidence from Thai Farmers
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Pronrumpa Kanjanasingh, Thittaya Ngamsang, and Preechaya Tajai*
🔗Read via: https://doi.org/10.12982/NLSC.2026.096
🔴𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
Although guidelines for pesticide use are widely recognized, prolonged application increases the risk of pesticide exposure. Consequently, studying pesticide exposure provides essential information for implementing precautionary measures in the area.

🎉 Congratulations Boonkhao et al. on your new publication!🛵𝚃𝚒𝚝𝚕𝚎: Motorcycle Riding-Related Functional Abilities among O...
14/09/2026

🎉 Congratulations Boonkhao et al. on your new publication!
🛵𝚃𝚒𝚝𝚕𝚎: Motorcycle Riding-Related Functional Abilities among Older Adults and Recommendations for Mitigating Risk-Related Problems on Rural Community Roads in Ubon Ratchathani Province, Thailand
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Laksanee Boonkhao*, Pongsak Rattanachaikunsopon, Papatsorn Tuphila, Orathai Chanthason, Chiraporn Labcom, Nittaya Chakhamrun, Jittar Tancharoen, Somjate Thongdamrongtham, Sitthichai Chaikhan, Wannee Kaewsuk, and Ueamporn Hernmek
🔗Read via: https://doi.org/10.12982/NLSC.2026.093
🔴𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
This study reveals that over 80% of older adults in rural Thailand lack adequate motorcycle riding-related functional abilities, particularly in brake reaction time and peripheral vision, significantly elevating accident risks. It highlights seven critical roadway risk points and proposes actionable safety interventions, including infrastructure improvements, safe-driving training, and integrating automated transport services to enhance safety for aging rural communities.

🎉 Congratulations Butdapheng et al. on your new publication!🦠𝚃𝚒𝚝𝚕𝚎: 𝐼𝑛 𝑉𝑖𝑡𝑟𝑜 Binding Inhibition and Molecular Docking An...
11/09/2026

🎉 Congratulations Butdapheng et al. on your new publication!
🦠𝚃𝚒𝚝𝚕𝚎: 𝐼𝑛 𝑉𝑖𝑡𝑟𝑜 Binding Inhibition and Molecular Docking Analysis of Baicalein, Scutellarein, and Gallic Acid against SARS-CoV-2 RBD–ACE2 Interaction
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Khunkhang Butdapheng, Polpan Sillapapibool, Worapol Sae-Foo, Waraporn Putalun, Waranyoo Phoolcharoen, and Rattanathorn Choonong*
🔗Read via: https://doi.org/10.12982/NLSC.2026.092
🟢𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
This study identifies flavonoids and polyphenols, particularly baicalein, scutellarein, and gallic acid, as promising inhibitors of SARS-CoV-2 RBD–ACE2 binding using integrated 𝑖𝑛 𝑣𝑖𝑡𝑟𝑜 and 𝑖𝑛 𝑠𝑖𝑙𝑖𝑐𝑜 approaches.

🎉 Congratulations Afnani et al. on your new publication!👱‍♀️𝚃𝚒𝚝𝚕𝚎: Expression-Guided Immunoinformatics Design of a Recom...
07/09/2026

🎉 Congratulations Afnani et al. on your new publication!
👱‍♀️𝚃𝚒𝚝𝚕𝚎: Expression-Guided Immunoinformatics Design of a Recombinant Multi-Epitope Vaccine Candidate for Triple-Negative Breast Cancer Incorporating a MyD88-Derived Immunomodulatory Domain
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Moh Royhan Afnani*, Volta Kellik Setiawan, and Anwar Rovik*
🔗Read via: https://doi.org/10.12982/NLSC.2026.091
🔵𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
This study presents an expression-guided recombinant multi-epitope vaccine candidate incorporating epitopes derived from MMP1, CXorf61/CT83, and COL11A1 into a single chimeric construct. The design integrates PADRE and a MyD88-derived exploratory immunomodulatory domain. Combined HLA class I and class II analysis predicted 99.36% worldwide population coverage, with coverage exceeding 90% in 14 of the 16 geographic regions evaluated.

🎉 Congratulations Estanislao et al. on your new publication!🍐𝚃𝚒𝚝𝚕𝚎: Process Optimization for Amylase-mediated Juice Extr...
04/09/2026

🎉 Congratulations Estanislao et al. on your new publication!
🍐𝚃𝚒𝚝𝚕𝚎: Process Optimization for Amylase-mediated Juice Extraction from Soursop (𝐴𝑛𝑛𝑜𝑛𝑎 𝑚𝑢𝑟𝑖𝑐𝑎𝑡𝑎)
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Jan Irish H. Estanislao*, Anna Rina B. Evangelista-Albacea, Ma. Cristina R. Ilano, Lloyd Earl L. Flandez, Joshua B. Benedicto, Romel M. Felismino, Sheba Mae M. Duque, and Katherine Ann T. Castillo-Israel
🔗Read via: https://doi.org/10.12982/NLSC.2026.082
🟢𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
Amylase-mediated extraction of soursop juice resulted in a better juice yield and influenced various physicochemical and bioactive properties of the juice. Particularly, it enhanced the bioaccessibility and extractability of resveratrol, a potent antioxidant found in soursop.

🎉 Congratulations Aeniah et al. on your new publication!🪻𝚃𝚒𝚝𝚕𝚎: Evaluation of Acute and Subchronic Toxicity of Butterfly...
31/08/2026

🎉 Congratulations Aeniah et al. on your new publication!
🪻𝚃𝚒𝚝𝚕𝚎: Evaluation of Acute and Subchronic Toxicity of Butterfly Pea (𝐶𝑙𝑖𝑡𝑜𝑟𝑖𝑎 𝑡𝑒𝑟𝑛𝑎𝑡𝑒𝑎 L.) Infusion on Histological Structure of Duodenum and Colon in Albino Rats 𝑅𝑎𝑡𝑡𝑢𝑠 𝑛𝑜𝑟𝑣𝑒𝑔𝑖𝑐𝑢𝑠 (Berkenhout, 1769)
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Siti Aeniah, Tia Apriliyani, Nur Ainun Oktavia Pusparini, Bambang Retnoaji, and Ardaning Nuriliani*
🔗Read via: https://doi.org/10.12982/NLSC.2026.085
🟣𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
In Indonesia, butterfly pea (𝐶𝑙𝑖𝑡𝑜𝑟𝑖𝑎 𝑡𝑒𝑟𝑛𝑎𝑡𝑒𝑎 L.) flowers are widely utilized as natural colorants in foods and beverages as well as in traditional medicine; however, scientific data regarding their safety, particularly with respect to the gastrointestinal tract, remain limited. Therefore, the present study constitutes a continuation of previous toxicity investigations on hematological profiles, organ function tests, and the histological structures of the liver, kidneys, and stomach. Accordingly, this study is expected to provide a more comprehensive assessment of the safety of butterfly pea flower infusion for daily consumption.

🎉 Congratulations Singhan et al. on your new publication!💊𝚃𝚒𝚝𝚕𝚎: Predictive Performance of a Priori Population-based Pre...
28/08/2026

🎉 Congratulations Singhan et al. on your new publication!
💊𝚃𝚒𝚝𝚕𝚎: Predictive Performance of a Priori Population-based Prediction and Linear Pharmacokinetic Calculation for Vancomycin Monitoring in Patients with Chronic Kidney Disease
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Wanchana Singhan, Thitichaya Penthinapong, Mingkwan Na Takuathung, Somratai Vadcharavivad, Nattapong Tidwong*
🔗Read via: https://doi.org/10.12982/NLSC.2026.090
🟢𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
A priori population-based prediction and linear pharmacokinetic calculation methods showed limited precision in predicting vancomycin trough concentrations in patients with chronic kidney disease (CKD). These findings highlight the importance of therapeutic drug monitoring, particularly during the initial days of therapy, to optimize efficacy and safety in this population.

🎉 Congratulations Lohitnavy et al. on your new publication!🥔𝚃𝚒𝚝𝚕𝚎: Total Phenolic, Flavonoid, and Coixol Contents, and 𝐼...
24/08/2026

🎉 Congratulations Lohitnavy et al. on your new publication!
🥔𝚃𝚒𝚝𝚕𝚎: Total Phenolic, Flavonoid, and Coixol Contents, and 𝐼𝑛 𝑣𝑖𝑡𝑟𝑜 α-amylase and α-glucosidase Inhibitory Activities of 𝐶𝑜𝑖𝑥 𝑙𝑎𝑐𝑟𝑦𝑚𝑎-𝑗𝑜𝑏𝑖 L. Seed Extracts
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Ornrat Lohitnavy, Khemmachat Pansooksan, Nalinthip Phitaknitiwoot, Ubonwan Onjek, Thatchaya Phoowanatdechawut, Sudthiworarak Kaewchompoo, Dumrongsak Pekthong, Piyarat Srisawang, and Supawadee Parhira*
🔗Read via: https://doi.org/10.12982/NLSC.2026.089
🟡𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
Job’s tears seeds, rich in phenolics, flavonoids, and coixol, exhibit promising α-glucosidase inhibitory activity, highlighting their potential as natural candidates for further investigation as antihyperglycemic agents.

🎉 Congratulations Thompradit et al. on your new publication!🌱𝚃𝚒𝚝𝚕𝚎: Enhancing Oxygen Transfer and Nitrogen Removal in Ve...
21/08/2026

🎉 Congratulations Thompradit et al. on your new publication!
🌱𝚃𝚒𝚝𝚕𝚎: Enhancing Oxygen Transfer and Nitrogen Removal in Vertical Up-flow Constructed Wetlands Using Intermittent Recirculation and Porous Media with 𝐶𝑎𝑛𝑛𝑎 𝑖𝑛𝑑𝑖𝑐𝑎
🖊𝙰𝚞𝚝𝚑𝚘𝚛: Kalanyoo Thompradit, Tararag Pincum, and Arunothai Jampeetong*
🔗Read via: https://doi.org/10.12982/NLSC.2026.088
🟢𝙺𝚎𝚢 𝚌𝚘𝚗𝚝𝚛𝚒𝚋𝚞𝚝𝚒𝚘𝚗𝚜:
𝐶𝑎𝑛𝑛𝑎 𝑖𝑛𝑑𝑖𝑐𝑎 plays a crucial role as an oxygen supplier, enhancing DO levels. Intermittent recirculation enhanced oxygen transfer, promoting BOD5 and N removal. Also, porous media (biochar and pumice) supported oxygen retention. However, extended recirculation time reduced TSS removal due to hydraulic disturbance. Thus, integrated plants, intermittent recirculation, and porous media enhanced system efficiency.

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