Ohio University Technology Transfer Office

Ohio University Technology Transfer Office Visit our website at: http://www.ohio.edu/research/tto/ And follow us at twitter: www.twitter.com/OUTechTransfer Check out our webpage on AUTM Global Technology Portal: http://gtp.autm.net/network/ohio-university/organization/summary

The Technology Transfer Office works with entrepreneurial and established business focuses on three broad strategic areas: *World Health and Quality of Life *Resource Sustainability *Societal, Culture, and Logistics Statistics: *Most widely known institution in the Appalachia *Ranked #4 nationally by Forbes magazine *Ranked #1 in Appalachia

Operating as usual

Focus areas for this competition included: Quantum Sensors, Synthetic Biology, Small Spacecraft Technology, Advancements...
08/17/2020

Focus areas for this competition included: Quantum Sensors, Synthetic Biology, Small Spacecraft Technology, Advancements in Mining, and X-Factor Innovations. AEIOU Scientific is developing instruments based on patent-pending Cortical Bone Mechanics Technology™ (CBMT) to help scientists measure what they could not measure before: accurate, non-invasive, direct functional measurements of structural mechanical properties of cortical bone in the ulnas of living people.

A big congratulations to Ohio University Innovation Center client company AEIOU Scientific and Gary Wakeford. AEIOU won the NASA iTech Ignite the Night Ohio competition!

https://aeiouscientific.com/

Congratulations to H. Bryan Riley, Nikita Gurudath and Mehmet Celenk on the issue of Patent 10,722,115, "Devices and Met...
07/31/2020
Automated Computer Classifier of Diabetic Retinopathy | Ohio University

Congratulations to H. Bryan Riley, Nikita Gurudath and Mehmet Celenk on the issue of Patent 10,722,115, "Devices and Methods for Classifying Diabetic and Macular Degeneration".

This computer-assisted technology is capable of detecting, classifying and monitoring diabetic retinopathy. Using machine learning techniques, this technology provides over 98% classification accuracy for discriminating healthy normal retina from non-proliferative diabetic #retinopathy and proliferative diabetic retinopathy.

For licensing opportunities, please contact Korie Counts at 740-593-0977 or [email protected].

https://bit.ly/TTO15015US
Russ College of Engineering and Technology
Ohio University Heritage College of Osteopathic Medicine
#maculardegeneration #diabeticretinopathy

Overview With an ever-increasing number of people being diagnosed with diabetes, it is imperative that new technologies be developed to effe

US Energy Secretary Brouillette cites success of CONSOL Energy & Ohio University project to develop coal-based composite...
07/01/2020
A deck made of coal? Let's explore that, says Energy Secretary Dan Brouillette

US Energy Secretary Brouillette cites success of CONSOL Energy & Ohio University project to develop coal-based composite decking to announce new $122M funding initiative for public-public partnerships for coal products.

Congrats Russ College of Engineering and Technology and Dr. Jason Trembly!

https://www.post-gazette.com/business/powersource/2020/06/27/A-deck-made-of-coal-Let-s-explore-that-says-Energy-Secretary-Dan-Brouillette/stories/202006270020

Mr. Brouillette used Consol’s experiments in turning coal into products as a backdrop to announce that $122 million in funding will be made available for private-public partnerships involved in such work.

We have five issued and three pending patents on a novel group of compounds that could be developed into the first targe...
06/12/2020
Treatment of Non-alcoholic Fatty Liver Disease | Ohio University

We have five issued and three pending patents on a novel group of compounds that could be developed into the first targeted therapy for #NAFLD, shifting the treatment paradigm to treating the disease itself rather than comorbities. https://bit.ly/TTONAFLD #NASHday #liverhealth

Ohio University Heritage College of Osteopathic Medicine
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Overview Non-alcoholic fatty liver disease (NAFLD) is a disease of excess fat accumulation in the liver of individuals with no history of alcohol abuse which can lead to hepatitis, sca

MARK2 is a  serine/threonine protein kinase that phosphorylates the  microtubule-associated protein tau. Unfortunately, ...
06/02/2020
Selective Kinase Inhibitor for the Treatment of Neurodegenerative Disorders | Ohio University

MARK2 is a serine/threonine protein kinase that phosphorylates the microtubule-associated protein tau. Unfortunately, dysfunctional MARK2 activity often leads to hyperphosphorylated tau isoforms that can aggregate into higher order filaments known as neurofibrillary tangles (NFTs). If left untreated, NFTs can compromise the structural integrity of neurons, leading to the onset of neurodegenerative disorders such as Alzheimer’s Disease and frontotemporal dementia.
Justin M. Holub and Robert Colvin at Ohio University recently developed a synthetic peptide capable of selectively inhibiting the MARK2-mediated phosphorylation of tau. This 13 residue peptide, known as tR1, inhibits tau phosphorylation at Ser262 in vitro and in cultured primary cortical neurons but does not inhibit other kinases that phosphorylate tau including GSK3b, CDK2 or CDK5.
This innovation represents the first step in the development of next-generation peptide-based therapeutics designed to treat neurodegenerative disorders such as #alzheimersdisease and frontotemporal dementia.
If you are interested in working with us to develop and commercialize this technology, contact Korie Counts at (740) 593-0977 or [email protected].
#neuroscience #dementia #alzheimers #therapeutics #drugdiscovery #research
Ohio University College of Arts & Sciences
Department of Chemistry and Biochemistry, Ohio University

Overview The human genome encodes more than 500 unique protein kinases, making them one of the largest superfamilies of signaling proteins. Protein kinases perform many diverse functions within the cell and serve to regulate a broad range of essential metabolic processes including signal transductio...

Donations are critical for maintaining the supply of blood products available to treat cancer, chronic illnesses, trauma...
05/29/2020
Method for Increasing the Storage Life of Donated Red Blood Cells | Ohio University

Donations are critical for maintaining the supply of blood products available to treat cancer, chronic illnesses, traumatic injuries and to replace blood lost during surgical procedures. Even after they are collected, red blood cells have a limited shelf life in storage - they must be used in 42 days or less. One way to increase the supply of usable red blood cells is to extend their shelf life.
Amir Farnoud at Ohio University has developed a method for doing just that. His current data show a 5x increase in shelf life, up to 210 days.
If you are interested in learning more about this technology or want to discuss licensing, please contact Korie Counts at (740) 593-0977 or [email protected].
#ohiouniversity #donateblood #giveblood #savelives #beahero https://bit.ly/TTO20026

Russ College of Engineering and Technology

Overview Every day in the U.S., approximately 36,000 units of red blood cells are needed. Blood donations are used to treat cancer, chronic illnesses, traumatic injuries and to replace blood lost during surgical procedures. These donations come from volunteers, an estimated 6.8 million in the U.S. e...

Ohio University faculty, graduate students, post doctoral fellows and staff scientists head back to the labs to investig...
05/28/2020
OHIO researchers returning to labs to research potential COVID-19 treatments

Ohio University faculty, graduate students, post doctoral fellows and staff scientists head back to the labs to investigate potential #COVID-19 treatments. Among them are Kelly McCall and Douglas Goetz, who were awarded a $100,000 FastGrant from Mercatus Center at George Mason University's Emergent Ventures to examine whether specific compounds can inhibit the cytokine storm associated with serious complications and death in coronavirus infections. Shiyong Wu(吴诗咏)is researching a bacterium that could potentially neutralize the coronavirus. Eric Masson will be conducting experiments on his existing cucurbituril-based system to see how well it binds to one of the key proteins involved in coronavirus replication. Jennifer Hines is utilizing software to investigate whether existing FDA-approved drugs could be repurposed to treat coronavirus, as well as designing novel synthetic compounds that could lead to new drugs to treat COVID-19's viral RNA.

Ohio University College of Arts & Sciences
Edison Biotechnology Institute
Russ College of Engineering and Technology
The Technology Transfer Office at Ohio University will work closely with the researchers involved in these projects to patent and commercialize and potential therapeutics.

#covid19 #coronavirustreatment #covid19research #covidresearch

Several Ohio University researchers have received permission for an early return to their labs to conduct research on potential treatments for COVID-19.

04/24/2020

US #patent 10,625,197 issued to Ohio University this week. It describes a novel precipitator and device that increases the removal of particulates from industrial exhaust due to the vibration of fine strings which maximize the contact with the particulates allowing them to be collected.

So much great work was on display at the #OUVirtualExpo yesterday. Please remember if you have a new #invention that we ...
04/10/2020

So much great work was on display at the #OUVirtualExpo yesterday. Please remember if you have a new #invention that we can still accept invention disclosures and NDA/MTA requests through our portals. https://ohio.edu/research/tto We're still working #TogetherAtHome

Ohio University Research News
04/09/2020

Ohio University Research News

Our Student Expo has moved online today! Look for the #OUVirtualExpo on Twitter and Instagram to see posts from Ohio University students that showcase their research, scholarship and creative work! More details: www.ohio.edu/studentexpo

Big congrats for Dr. Trembly on his $1.5M DOE award to develop engineered composite decking boards from coal. A new use ...
04/06/2020
OHIO Engineering researcher and team receive $2 million to create coal composites

Big congrats for Dr. Trembly on his $1.5M DOE award to develop engineered composite decking boards from coal. A new use for coal and a sustainable and energy-efficient alternative to wood plastics for building materials is an exciting development.
Russ College of Engineering and Technology
https://www.ohio.edu/news/2019/09/ohio-engineering-researcher-and-team-receive-2-million-create-coal-composites

The U.S. Department of Energy (DOE) has awarded $1.5 million to an Ohio University professor to develop engineered composite decking boards from coal.

#Patent 10,591,017 issued March 20 for a Resetting Semi-Active Stiffness Damper invented by Dr. Ken Walsh that utilizes ...
04/03/2020

#Patent 10,591,017 issued March 20 for a Resetting Semi-Active Stiffness Damper invented by Dr. Ken Walsh that utilizes a system that achieves resetting without the need for a complex feedback control system, enhancing the reliability of the damper during a seismic event. Find out more here: http://bit.ly/TTO12015 Russ College of Engineering and Technology

Congratulations to Doug Goetz for being elected to the American Institute for Medical and Biological Engineering College...
03/31/2020
OHIO professor named to top two percent of medical, biological engineers

Congratulations to Doug Goetz for being elected to the American Institute for Medical and Biological Engineering College of Fellows.

In addition to his accomplishments in the laboratory and the classroom, Dr. Goetz has been part of 17 invention disclosures to the Ohio University Technology Transfer Office. These have translated into 47 patent applications, of which 9 are currently active or issued.

If you are interested in taking a look at the novel therapeutic compounds that Dr. Goetz has helped develop, including those with potential to treat #NAFLD, check out our Technologies page (https://lnkd.in/ex7fBTU) or contact Korie Counts for further details ([email protected]; 740-593-0977).

Ohio University Professor of Chemical and Biomolecular Engineering Doug Goetz has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows.

Scientists Ohio University discovered that the administration of peptide FSP27 improves insulin signaling. This decrease...
03/27/2020
Therapeutic Peptide for Obesity and Diabetes | Ohio University

Scientists Ohio University discovered that the administration of peptide FSP27 improves insulin signaling. This decreases insulin resistance, optimizes fat storage/breakdown, reduces circulatory free fatty acids and improves blood glucose levels.

Recombinant FSP27 can be formulated as a therapeutic for targeting obesity and its underlying causes. It is envisioned that this treatment will dramatically improve the health and quality of life for millions of adults and children suffering from the effects of obesity, including type 2 diabetes. Ohio University is seeking a collaborative partner interested in pursuing a novel treatment for tackling this debilitating condition.

https://bit.ly/TTO-17021 #diabetesalertday

Overview Obesity is a significant public health problem. Statistics show that 70% of U.S. adults are considered overweight or obese and 17% of children under the age of 19 have obesity 1. Being overweight or obese puts a person at risk for many other health problems, including heart disease, type 2....

03/03/2020

Issued today, US #Patent 10,577,699 "Electrochemical Conversion of Lignin to Industrial Chemicals".
Russ College of Engineering and Technology's John Staser presents a method of utilizing biorefinery waste as a renewable raw material in useful industrial chemicals. Contact us for licensing info.

02/26/2020
First Full-Vehicle Test of Ohio University’s Autonomous Vehicle Controller

We've mentioned that OHIO's autonomous vehicle control had been tested recently in a full size vehicle and we are finally able to share the video!

On January 17, 2020, Ohio University’s autonomous vehicle controller, dubbed DriveMate™, was tested for the first time on a full-size vehicle. The test was performed by the Advanced Engineering Division of Roush Industries, Inc on a Kia Soul EV with several path profiles, including straight line, circle, U-turn, figure-8, lane-shifting, sinusoidal, and a 4-pedal rose-curve. Shown in this video is the test on the rose-curve path, which is typically found at highway intersection ramps. The control system is developed by the Ohio University student organization Professional Autonomous Vehicle Engineers (Ohio University-PAVE). The development and test are funded by the School of Electrical Engineering and Computer Science (EECS), Russ College of Engineering and Technology, Office of the Vice President for Research and Creative Activity, Technology Transfer Office, and a Technology Validation and Testing Fund (TVSF) Phase 1 grant from the Ohio Third Frontier.

Ohio University Research News

On January 17, 2020, Ohio University’s autonomous vehicle controller, dubbed DriveMate™, was tested for the first time on a full-size vehicle. The test was p...

Ohio University Student Expo
02/18/2020

Ohio University Student Expo

Imagine discovering a compound that has the potential to create therapeutic opportunities for a plethora of diseases pot...
02/10/2020
Modulating the Activity of GSK-3 to Treat Multiple Pathologies | Ohio University

Imagine discovering a compound that has the potential to create therapeutic opportunities for a plethora of diseases potentially including diabetes, cancers, asthma, neurodegenerative diseases (ex. Alzheimer’s disease) and psychiatric disorders. Ohio University professors from three different colleges, along with the support of many students, faculty members and staff, may have just done that. http://bit.ly/39rjK7Z
Contact Korie Counts for licensing or research collaboration opportunities involving this family of compounds. http://bit.ly/TTOGSK3
Heritage College of Osteopathic Medicine Russ College of Engineering and Technology Ohio University College of Arts & Sciences

Overview Glycogen synthase kinase-3 (GSK-3) is a protein kinase that has been implicated in a number of pathologies, including bipolar disorder, Alzheimer’s disease, schizophrenia, pathological inflammation, and diabetes. Identifying selective inhibitors for GSK-3 to aid in the treatment of these ...

Issued today, #patent 10,550,945, describes shutdown valves capable of operating in a second mode with a bypass feature ...
02/04/2020
Emergency Shutdown Valve with Bypass Features | Ohio University

Issued today, #patent 10,550,945, describes shutdown valves capable of operating in a second mode with a bypass feature that allows a flow of material to pass through while the valve is otherwise closed to enable testing without interrupting processes. http://bit.ly/TTO12017 This technology was developed by 2013 Ohio University Department of Physics and Astronomy Ph.D. Azamat Orazbayev. For information on licensing this technology, please contact Mark Foley [email protected].

Overview A common and major problem associated with the testing of emergency shutdown valves is the very stoppage of flow that the valves are designed to produce. While it is obviously required that an emergency shutdown valve stop a flow of material in a true emergency shutdown situation, testing o...

White House official gets demo of Ohio University's virtual reality #Narcan project. http://bit.ly/2Ob40xA Currently und...
01/30/2020
White House official gets demo of virtual reality Narcan project

White House official gets demo of Ohio University's virtual reality #Narcan project. http://bit.ly/2Ob40xA Currently under development by Ohio University School of Nursing researchers and GRID Lab. Contact us for licensing information.

A White House official in Athens Friday morning demonstrated a virtual-reality simulation designed by faculty members and students at Ohio University’s GRID Lab.

This week, Ohio University was issued US Patent 10,544,503 for a simple and scalable method of producing defect-free gra...
01/24/2020
Low-Cost Production of Graphene from Coal | Ohio University

This week, Ohio University was issued US Patent 10,544,503 for a simple and scalable method of producing defect-free graphene from inexpensive and widely available coal, eliminating the dependence on graphite. Contact us for licensing information. http://bit.ly/TTO12018

Overview Exploitation of the unique properties of graphene for new commercial applications is occurring at a phenomenal rate. However, current methods of graphene production are inefficient and expensive and do not provide a commercial supply to meet expected future demand. An industrially scalable....

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