Ohio University Technology Transfer Office

08/17/2020

Focus areas for this competition included: Quantum Sensors, Synthetic Biology, Small Spacecraft Technology, Advancements in Mining, and X-Factor Innovations. AEIOU Scientific is developing instruments based on patent-pending Cortical Bone Mechanics Technology™ (CBMT) to help scientists measure what they could not measure before: accurate, non-invasive, direct functional measurements of structural mechanical properties of cortical bone in the ulnas of living people.

A big congratulations to Ohio University Innovation Center client company AEIOU Scientific and Gary Wakeford. AEIOU won the NASA iTech Ignite the Night Ohio competition!

https://aeiouscientific.com/

07/31/2020

Congratulations to H. Bryan Riley, Nikita Gurudath and Mehmet Celenk on the issue of Patent 10,722,115, "Devices and Methods for Classifying Diabetic and Macular Degeneration".

This computer-assisted technology is capable of detecting, classifying and monitoring diabetic retinopathy. Using machine learning techniques, this technology provides over 98% classification accuracy for discriminating healthy normal retina from non-proliferative diabetic and proliferative diabetic retinopathy.

For licensing opportunities, please contact Korie Counts at 740-593-0977 or [email protected].

https://bit.ly/TTO15015US
Russ College of Engineering and Technology
Ohio University Heritage College of Osteopathic Medicine

Overview With an ever-increasing number of people being diagnosed with diabetes, it is imperative that new technologies be developed to effe

07/01/2020

US Energy Secretary Brouillette cites success of CONSOL Energy & Ohio University project to develop coal-based composite decking to announce new $122M funding initiative for public-public partnerships for coal products.

Congrats Russ College of Engineering and Technology and Dr. Jason Trembly!

Mr. Brouillette used Consol’s experiments in turning coal into products as a backdrop to announce that $122 million in funding will be made available for private-public partnerships involved in such work.

06/12/2020

We have five issued and three pending patents on a novel group of compounds that could be developed into the first targeted therapy for , shifting the treatment paradigm to treating the disease itself rather than comorbities. https://bit.ly/TTONAFLD

Ohio University Heritage College of Osteopathic Medicine
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Overview Non-alcoholic fatty liver disease (NAFLD) is a disease of excess fat accumulation in the liver of individuals with no history of alcohol abuse which can lead to hepatitis, sca

06/02/2020

MARK2 is a serine/threonine protein kinase that phosphorylates the microtubule-associated protein tau. Unfortunately, dysfunctional MARK2 activity often leads to hyperphosphorylated tau isoforms that can aggregate into higher order filaments known as neurofibrillary tangles (NFTs). If left untreated, NFTs can compromise the structural integrity of neurons, leading to the onset of neurodegenerative disorders such as Alzheimer’s Disease and frontotemporal dementia.
Justin M. Holub and Robert Colvin at Ohio University recently developed a synthetic peptide capable of selectively inhibiting the MARK2-mediated phosphorylation of tau. This 13 residue peptide, known as tR1, inhibits tau phosphorylation at Ser262 in vitro and in cultured primary cortical neurons but does not inhibit other kinases that phosphorylate tau including GSK3b, CDK2 or CDK5.
This innovation represents the first step in the development of next-generation peptide-based therapeutics designed to treat neurodegenerative disorders such as and frontotemporal dementia.
If you are interested in working with us to develop and commercialize this technology, contact Korie Counts at (740) 593-0977 or [email protected].

Ohio University College of Arts & Sciences
Department of Chemistry and Biochemistry, Ohio University

Overview The human genome encodes more than 500 unique protein kinases, making them one of the largest superfamilies of signaling proteins. Protein kinases perform many diverse functions within the cell and serve to regulate a broad range of essential metabolic processes including signal transductio...

05/29/2020

Donations are critical for maintaining the supply of blood products available to treat cancer, chronic illnesses, traumatic injuries and to replace blood lost during surgical procedures. Even after they are collected, red blood cells have a limited shelf life in storage - they must be used in 42 days or less. One way to increase the supply of usable red blood cells is to extend their shelf life.
Amir Farnoud at Ohio University has developed a method for doing just that. His current data show a 5x increase in shelf life, up to 210 days.
If you are interested in learning more about this technology or want to discuss licensing, please contact Korie Counts at (740) 593-0977 or [email protected].
https://bit.ly/TTO20026

Russ College of Engineering and Technology

Overview Every day in the U.S., approximately 36,000 units of red blood cells are needed. Blood donations are used to treat cancer, chronic illnesses, traumatic injuries and to replace blood lost during surgical procedures. These donations come from volunteers, an estimated 6.8 million in the U.S. e...

05/28/2020

Ohio University faculty, graduate students, post doctoral fellows and staff scientists head back to the labs to investigate potential -19 treatments. Among them are Kelly McCall and Douglas Goetz, who were awarded a $100,000 FastGrant from Mercatus Center at George Mason University's Emergent Ventures to examine whether specific compounds can inhibit the cytokine storm associated with serious complications and death in coronavirus infections. Shiyong Wu（吴诗咏）is researching a bacterium that could potentially neutralize the coronavirus. Eric Masson will be conducting experiments on his existing cucurbituril-based system to see how well it binds to one of the key proteins involved in coronavirus replication. Jennifer Hines is utilizing software to investigate whether existing FDA-approved drugs could be repurposed to treat coronavirus, as well as designing novel synthetic compounds that could lead to new drugs to treat COVID-19's viral RNA.

Ohio University College of Arts & Sciences
Edison Biotechnology Institute
Russ College of Engineering and Technology
The Technology Transfer Office at Ohio University will work closely with the researchers involved in these projects to patent and commercialize and potential therapeutics.

Several Ohio University researchers have received permission for an early return to their labs to conduct research on potential treatments for COVID-19.

04/30/2020

"As part of this research, they have developed some compounds that are highly effective at inhibiting the action of an enzyme known as GSK-3." Check out this technology and its other applications here http://bit.ly/TTOGSK3

Faculty researchers from Ohio University have received a $100,000 grant to investigate possible treatments for mitigating the severity of COVID-19.

04/24/2020

US 10,625,197 issued to Ohio University this week. It describes a novel precipitator and device that increases the removal of particulates from industrial exhaust due to the vibration of fine strings which maximize the contact with the particulates allowing them to be collected.

04/10/2020

So much great work was on display at the yesterday. Please remember if you have a new that we can still accept invention disclosures and NDA/MTA requests through our portals. https://ohio.edu/research/tto We're still working

04/09/2020

Our Student Expo has moved online today! Look for the on Twitter and Instagram to see posts from Ohio University students that showcase their research, scholarship and creative work! More details: www.ohio.edu/studentexpo

04/06/2020

Big congrats for Dr. Trembly on his $1.5M DOE award to develop engineered composite decking boards from coal. A new use for coal and a sustainable and energy-efficient alternative to wood plastics for building materials is an exciting development.
Russ College of Engineering and Technology

The U.S. Department of Energy (DOE) has awarded $1.5 million to an Ohio University professor to develop engineered composite decking boards from coal.