12/11/2025
Very exciting findings on glioblastoma by one of our NSIP labs!
Glioblastoma is the deadliest form of brain cancer. A new study is bringing hope that it could be survivable.
The publication in The Lancet Oncology, led by Dr. Graeme Woodworth, Professor and Chair of Neurosurgery at the University of Maryland School of Medicine and Neurosurgeon-In-Chief at UMMC, shows promising results.
The study is the first to find a potential survival benefit to adding focused ultrasound to standard chemotherapy.
The key advancement is getting treatment directly into the brain. The blood–brain barrier normally blocks toxins but it also blocks most therapies. Focused ultrasound temporarily opens this barrier, which allows chemotherapy to enter the brain and target the dangerous cancer cells that remain after standard treatment. The barrier then closes again.
The goal is to use focused ultrasound to treat tumors more effectively, monitor for signs of regrowth, and re-treat patients when needed. This form of treatment is currently only available in clinical trials and work still needs to be done to confirm these results in larger studies, but Dr. Woodworth says this is an exciting step forward.
Read the full story in The Baltimore Banner: https://www.thebanner.com/community/public-health/focused-ultrasound-study-glioblastoma-brain-cancer-LAGEPSTQ2RBPHJGX7VG7PFNXQM/