Knoepfler Lab

08/30/2026

Weekly & reads: aging clocks under the gun, more on R3 Stem warning, Capricor update, FDA perinatal tissue setback https://ipscell.com/2026/08/weekly-reads-aging-clocks-under-the-gun-more-on-r3-stem-warning-capricor-update-fda-perinatal-tissue-setback

Biologist discusses weekly reads in the field: aging clocks under the gun, more on R3 Stem warning, ISSCR, FDA set back.

08/28/2026

Wow, after 8 years! Key FDA victory on stem cell clinics: permanent injunction against Cell Surgical Network, et al. (chain of dozens of clinics) https://ipscell.com/2026/08/key-fda-victory-on-stem-cell-clinics-permanent-injunction-against-cell-surgical-network-et-al What happens now? Implications for the stem cell clinic arena and future of the FDA

Biologist discusses how the FDA prevails with permanent injunction against California Stem Cell Treatment Center, Cell Surgical Network.

08/26/2026

Big implications for biologics/clinic arena from FDA warning to R3 Stem Cell https://ipscell.com/2026/08/big-implications-for-clinic-arena-from-fda-warning-to-r3-stem-cell-david-greene-associated-firms Letter relates to exosomes & birth related cells being defined as drugs by FDA, CGMP concerns also noted. What happens next with this big group of clinics?

Cell biologist discusses new FDA warning to stem cell clinic firm R3 Stem Cell and why there is reason for major concern here.

08/23/2026

Weekly & reads: Heidi Overton FDA commish nominee, NASA stem cells, aged brain organoids, cautious Nature iPS cell editorial

Biologist discusses weekly regenerative medicine news including that Heidi Overton is the frontrunner to lead the FDA.

08/19/2026

Article on longevity & David Sinclair provides new insights including into his motivations but has issues re: science history https://ipscell.com/2026/08/article-on-longevity-david-sinclair-provides-new-insights-but-has-issues/ big question: does longevity space have altruism as a key driver?

I’ve been debating whether to unfollow longevity enthusiasts David Sinclair and Bryan Johnson on X. I find their posts about various anti-aging efforts to be fascinating on one level but also very unsettling. For one thing, some posts seem close to medical advice to the public, yet neither is a ph...

08/09/2026

Weekly regenerative med & reads: DOJ claims $95M perinatal tissue fraud (amniotic membrane), 6-year gray market peptide related prison term, ALS patient story, worrisome MRT clinics trying to boost fertility via 3-parent IVF

Weekly stem cell reads: DOJ claims $85M perinatal tissue fraud, 6-year peptide prison term, ALS patient story, worrisome MRT clinics.

08/05/2026

Midweek stem cell & regenerative medicine news: another FDA warning & Florida state stem cell law problems already, bigger concerns about many such state laws, non-independent FDA https://ipscell.com/2026/08/midweek-news-another-fda-warning-florida-state-stem-cell-law-problems-already

Professor discusses another FDA warning & bad stuff going on with the Florida state stem cell law used as cover.

08/02/2026

Weekly reads: FDA warning interesting in the context of RFK Jr., Capricor pub and AdCom on same day, stem cells can count, hydra regeneration https://ipscell.com/2026/08/weekly-reads-fda-warning-capricor-pub-vs-adcom-stem-cells-can-count-hydra-regeneration

07/29/2026

More farce or tragedy? What's ahead after RFK Jr.'s PCAC kangaroo meeting green lit risky peptides. Could something similar happen with ? https://ipscell.com/2026/07/more-farce-or-tragedy-whats-ahead-after-rfk-jr-s-pcac-kangaroo-meeting-green-lit-risky-peptides Interesting to compare to today's CTGTAC mtg

Biologist describes how RFK Jr.'s kangaroo meeting of PCAC green lights pop peptides no matter despite legit FDA staff concerns.

07/26/2026

Weekly reads: new insights into MYC phosphorylation, reversing aging proteins, mitochondria don’t like space, & that peptide committee https://ipscell.com/2026/07/weekly-reads-myc-phosphorylation-reverse-protein-aging-mitochondria-dont-like-space-that-peptide-committee

Professor discusses novel MYC phosphorylation, reverse protein aging, peptide committee mainly gives RFK Jr. what he wants