06/04/2026
New research on microplastics from the UC Davis Department of Nutrition and Department of Chemistry explores how microplastics may interact with biological systems at the molecular level.
In a mice model, researchers examined oral exposure to polystyrene (a common plastic that can break down into micro- and nanoplastics) and used advanced imaging tools (MALDI MSI + TIMS) to track where these particles go and how organs and tissues respond.
Findings show distinct, organ-specific changes in lipid metabolism:
• Stomach showed signs of epithelial stress
• Liver had altered lipid processing and indications of adjustments to maintain stability
• Heart exhibited disrupted membrane-related lipid pathways
Together, the results suggest microplastics may influence biological systems in more complex and tissue-specific ways than previously understood.
Learn more: https://onlinelibrary.wiley.com/doi/10.1002/anie.6528604
College of Agricultural and Environmental Sciences, UC Davis
UC Davis Health
Image description: Stacks of white styrofoam takeout containers on a brown surface. Image text: Microplastics don’t just pass through. They may change how our organs function.