08/27/2026
How do cells know which genes to turn on? π§¬
A team led by researchers at the Research Institute of Molecular Pathology in Vienna, together with the laboratory of Associate Professor Evgeny Kvon at the UC Irvine Charlie Dunlop School of Biological Sciences, used deep machine learning to design artificial DNA switches that successfully activated genes in specific tissues of living mouse embryos.
The findings could help scientists better understand development and pave the way for more targeted gene therapies.
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A transgenic mouse embryo in which AI-designed regulatory DNA sequences drive gene expression in the forebrain (red) and in the midbrain (green). Image credit: [β¦]