10/13/2026
Researchers at the Cornell University College of Veterinary Medicine and the Baker Institute for Animal Health have documented the first-ever molecular characterization of Marfan syndrome in domestic cats — published in the September 19 issue of Scientific Reports. 🔬
Meet Gary and Shaggy 🐾 feline siblings whose unusually long limbs as kittens, combined with later eye abnormalities and an enlarged aorta, led veterinarians to suspect Marfan syndrome, a rare connective tissue disorder best known in humans (affecting ~1 in 4,000 people). This marks the first documented case in cats!
Through genetic sequencing, the team discovered that both brothers carried two altered copies of the FBN1 gene — which codes for fibrillin-1, a key building block of connective tissue found in blood vessels, bones, skin, and eyes. 🐈
This discovery brought together veterinary specialists and geneticists from Cornell, Ghent University (Belgium), the University of Pennsylvania, and The Schwarzman Animal Medical Center in NYC. 🌎
Read more: https://www.vet.cornell.edu/about-us/news/20260922/first-known-cases-feline-marfan-syndrome-discovered-cat-siblings