08/26/2026
Miraculous medicine 🧠🧠🧠
In 1995, Christina Santhouse was eight years old when she developed Rasmussen’s encephalitis, a rare neurological disorder that causes progressive inflammation and destruction of one side of the brain.
Her seizures became increasingly severe. At their peak, she was experiencing more than 150 seizures a day, and medication was unable to control them.
Doctors at Johns Hopkins recommended a hemispherectomy, a major operation in which the affected cerebral hemisphere is removed. In Christina’s case, surgeons removed the right hemisphere in a procedure that lasted about 14 hours.
The operation stopped the seizures, but it left Christina with significant physical effects. She lost most of the useful movement in her left hand, had weakness on the left side of her body, and lost part of her visual field. She subsequently underwent extensive rehabilitation.
Because the surgery was performed during childhood, her remaining left hemisphere was able to reorganize some functions normally associated with the removed hemisphere. This kind of neuroplasticity is one reason hemispherectomy can produce surprisingly good cognitive and functional outcomes in children with severe epilepsy.
Christina continued her education and became an honors student. She obtained her driver's license at 17 and later attended Misericordia University, completing both undergraduate and master's degrees in five years. She went on to work as a speech-language pathologist.
Her case is an example of the brain’s capacity for functional reorganization after major injury or surgery. It also illustrates the limitations of that adaptation: Christina achieved a high level of independence, but she continued to live with permanent motor and visual impairments following the removal of her right hemisphere.