12/19/2023
PhD Epidemiology Graduate Fall 2023: Adam Ward
Adam's research interests are: HIV persistence, HIV cure, adaptive immunity, LGBTQ health
Adam's dissertation title is "Study on HIV Reservoir Size, HIV-Specific Immune Response Trends, and Inflammation, and their Relationships, in People Living with HIV on Long-Term Antiretroviral Therapy"
Adam Ward’s research broadly focuses on better understanding mechanisms of HIV persistence despite antiretroviral therapy, as well as associated comorbidities, and immune-based HIV cure strategies. Adam successfully defended his dissertation titled “Study on HIV Reservoir Size, HIV-Specific Immune Response Trends, and Inflammation, and their Relationships, in People Living with HIV on Long-Term Antiretroviral Therapy” on August 11th, 2023. His dissertation work was comprised of 3 separate but related manuscripts: i) a cross-sectional study on host and viral factors impacting measures of HIV persistence in two cohorts of PLWH on long-term therapy; ii) a longitudinal analysis on the dynamics of HIV-specific T cell responses and associations with HIV persistence measures in a cohort of PLWH on long-term therapy; and iii) a cross-sectional analysis on levels of clinically relevant inflammatory and immune activation biomarkers in this cohort, and the three-way relationship between these biomarkers with HIV-specific adaptive immune responses and measures of HIV persistence. Adam has published his dissertation work in the journals JCI Insight and AIDS, and has presented this work at CROI 2020, CROI 2022, and AIDS 2022 conferences. He has also contributed to 15 related publications during his PhD, including leading a review on “Immunological Approaches to HIV Cure.” Adam completed a B.Sc. in Environmental Sciences (2011) and an M.Sc. in Biomedical Sciences (2015) from North Carolina State University, and also completed George Washington University's Graduate Certificate program in LGBT Health Policy & Practice (2015) before joining the Ph.D. program in Epidemiology in the Milken Institute School of Public Health in 2016. He currently works as the Program Manager and Biostatistician for the Research Enterprise to Advance a Cure for HIV based at Weill Cornell Medicine.