08/18/2026
Ph.D. Defense Success for Lucas Guttieres! 🎉🐊
Lucas Guttieres, a graduate student in the Department of Biology and supervised by Mark Q. Martindale, successfully defended his PhD dissertation on July 15, 2026, and walked in the University of Florida doctoral graduation ceremony on August 7.
Dr. Guttieres was interested in the emergence of multicellularity that required the evolution of new mechanisms mediating cell adhesion, communication, and coordination. Among the proposed molecular candidates that may have contributed to the transition from unicellularity to multicellularity, the protein β-catenin is of particular interest because of its dual role as a structural component of the cadherin-catenin complex (CCC) and as a transcriptional co-regulator in the canonical Wnt (cWnt) signaling pathway.
Although these functions are well-characterized in bilaterian animals, their evolutionary origins remain poorly understood. Early-diverging animal lineages provide a valuable framework for investigating the ancestral functions of β-catenin and the emergence of its interaction networks. In his thesis, Dr. Guttieres focused on the evolutionary history of β-catenin interaction networks in the ctenophore species Mnemiopsis leidyi with a particular focus on its adhesive and nuclear functions.
https://www.whitney.ufl.edu/news--events/news/whitney-articles/2026/phd-defense-lucas-guttieres.html