07/09/2026
We – the AIMultimediaLab, coordinated by Prof. Bogdan Ionescu – are excited to share our latest research in Artificial Intelligence and Deep Learning for the diagnosis and staging of membranous glomerulonephritis from electron microscopy images.
In this work, we developed a two-stage Deep Learning model based on vision transformer networks to detect membrane regions and subsequently classify them according to the stage of membranous glomerulonephritis, a major cause of nephrotic syndrome in adults. The proposed model achieved an accuracy of 92.31%, sensitivity of 92.40%, and specificity of 91.67%, while demonstrating strong performance on an independent external dataset. The results highlight the model’s robustness and generalizability, demonstrating the potential of AI-assisted electron microscopy to support more accurate and interpretable MN staging and its integration into clinical diagnostic workflows.
See “Two-Stage Deep Learning Networks for Diagnosing and Staging Membranous Glomerulonephritis from Electron Microscopy Images”, M.G. Constantin, G. Terinte-Balcan, I.M. Lambrescu, T.E. Fertig, O.B. Lazăr, A.-G. Andrei, N. Petre, B. Ionescu, and M. Gherghiceanu, Laboratory Investigation, 106(8), Impact Factor 4.1, 2026. Read the full article here: https://doi.org/10.1016/j.labinv.2026.106141.
Universitatea POLITEHNICA din București Universitatea de Medicina si Farmacie "Carol Davila" Institutul Național Victor Babeș